Cannabis / Marijuana
Cannabis sativa / indica
A plant with a long medicinal history and growing modern evidence: best-supported for chronic pain, chemotherapy nausea, appetite (in wasting illness), and muscle spasticity (MS); purified CBD is FDA-approved for certain rare epilepsies.
Traditional use (indigenous-americas, tcm, ayurveda): A plant with a long medicinal history and growing modern evidence: best-supported for chronic pain, chemotherapy nausea, appetite (in wasting illness), and muscle spasticity (MS); purified CBD is FDA-approved for certain rare epilepsies.
A plant with a long medicinal history and growing modern evidence: best-supported for chronic pain, chemotherapy nausea, appetite (in wasting illness), and muscle spasticity (MS); purified CBD is FDA-approved for certain rare epilepsies.
Active constituents are under study; evidence ranges from traditional use to preliminary human trials.
- Chronic and neuropathic pain
- Chemotherapy-induced nausea/appetite
- Spasticity (multiple sclerosis)
- CBD for specific seizure disorders
Evidence strength: mixed.
- See the evidence level above
- Impairment, dependence, anxiety/paranoia, lung harm if smoked; cannabis use disorder is real; risks to adolescent brain development and in pregnancy; drug interactions (sedatives, blood thinners).
- Pregnancy/breastfeeding
- Adolescents (developing brain)
- Personal/family history of psychosis
- Operating vehicles/machinery
Impairment, dependence, anxiety/paranoia, lung harm if smoked; cannabis use disorder is real; risks to adolescent brain development and in pregnancy; drug interactions (sedatives, blood thinners).
May interact with prescription medications — review with a clinician if you take any.
Use caution in pregnancy, breastfeeding, for children, and with chronic disease unless cleared by a clinician.
Choose reputable, tested suppliers; correct identification is essential for wild-harvested plants.
Real, evidence-backed medical uses alongside real risks and wide-varying legality — an honest, sober look, not hype in either direction. Know your local laws and involve a clinician.