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Traditional part

Cayenne

Capsicum annuum

Stronger human evidenceModerate — observe cautionsInteractions: ModeratePregnancy: Caution
Benefits summary

A hot pepper whose capsaicin has solid evidence in topical creams for nerve and joint pain, and folk use for circulation.

Traditional & historical use

Traditional use (household, indigenous-americas): A hot pepper whose capsaicin has solid evidence in topical creams for nerve and joint pain, and folk use for circulation.

Modern claims

A hot pepper whose capsaicin has solid evidence in topical creams for nerve and joint pain, and folk use for circulation.

How it may work

Active constituents are under study; evidence ranges from traditional use to preliminary human trials.

Benefit–risk at a glance
Potential benefits
  • Topical capsaicin for nerve/joint pain
Most credible evidence

Evidence strength: stronger human.

Key uncertainties
  • See the evidence level above
Known risks
  • Burns skin/eyes and irritates the stomach; topical capsaicin stings before it helps; wash hands well.
Who should avoid
  • Broken skin
  • Eyes/mucous membranes
Risks

Burns skin/eyes and irritates the stomach; topical capsaicin stings before it helps; wash hands well.

Interactions

May interact with prescription medications — review with a clinician if you take any.

Special populations

Use caution in pregnancy, breastfeeding, for children, and with chronic disease unless cleared by a clinician.

Sourcing & growing

Choose reputable, tested suppliers; correct identification is essential for wild-harvested plants.

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