All herbs
Traditional part

Comfrey

Symphytum officinale

Limited human evidenceHigh caution — significant risksInteractions: ModeratePregnancy: Avoid
Benefits summary

The classic 'knitbone' — allantoin-rich leaf/root used topically to speed healing of bruises, sprains, and wounds.

Traditional & historical use

Traditional use (european-folk): The classic 'knitbone' — allantoin-rich leaf/root used topically to speed healing of bruises, sprains, and wounds.

Modern claims

The classic 'knitbone' — allantoin-rich leaf/root used topically to speed healing of bruises, sprains, and wounds.

How it may work

Active constituents are under study; evidence ranges from traditional use to preliminary human trials.

Benefit–risk at a glance
Potential benefits
  • The classic 'knitbone' — allantoin-rich leaf/root used topically to speed healing of bruises, sprains, and wounds.
Most credible evidence

Evidence strength: limited human.

Key uncertainties
  • See the evidence level above
Known risks
  • Contains pyrrolizidine alkaloids that are LIVER-TOXIC if taken internally; topical use on broken skin and any internal use are discouraged.
Who should avoid
  • Internal use
  • Broken skin
  • Pregnancy/breastfeeding
  • Liver disease
Risks

Contains pyrrolizidine alkaloids that are LIVER-TOXIC if taken internally; topical use on broken skin and any internal use are discouraged.

Interactions

May interact with prescription medications — review with a clinician if you take any.

Special populations

Use caution in pregnancy, breastfeeding, for children, and with chronic disease unless cleared by a clinician.

Sourcing & growing

Choose reputable, tested suppliers; correct identification is essential for wild-harvested plants.

Dr. Bull's read

A genuinely useful topical for intact skin — but never swallow it.

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